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Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function

Human mutations in or variants of TBX20 are associated with congenital heart disease, cardiomyopathy, and arrhythmias. To investigate whether cardiac disease in patients with these conditions results from an embryonic or ongoing requirement for Tbx20 in myocardium, we ablated Tbx20 specifically in a...

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Bibliographische Detailangaben
Hauptverfasser: Shen, Tao, Aneas, Ivy, Sakabe, Noboru, Dirschinger, Ralf J., Wang, Gang, Smemo, Scott, Westlund, John M., Cheng, Hongqiang, Dalton, Nancy, Gu, Yusu, Boogerd, Cornelis J., Cai, Chen-leng, Peterson, Kirk, Chen, Ju, Nobrega, Marcelo A., Evans, Sylvia M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2011
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223071/
https://ncbi.nlm.nih.gov/pubmed/22080862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59472
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