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TIEG1-NULL OSTEOCYTES DISPLAY DEFECTS IN THEIR MORPHOLOGY, DENSITY AND SURROUNDING BONE MATRIX

Through the development of TGFβ-inducible early gene-1 (TIEG1) knockout (KO) mice, we have demonstrated that TIEG1 plays an important role in osteoblast-mediated bone mineralization, and in bone resistance to mechanical strain. To further investigate the influence of TIEG1 in skeletal maintenance, o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Haddad, Oualid, Hawse, John R., Subramaniam, Malayannan, Spelsberg, Thomas C., Bensamoun, Sabine F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222944/
https://ncbi.nlm.nih.gov/pubmed/22121306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1142/S0218957709002304
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