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Overexpression of DMP1 Accelerates Mineralization and Alters Cortical Bone Biomechanical Properties in Vivo

Dentin matrix protein-1 (DMP1) is a key regulator of biomineralization. Here, we examine changes in structural, geometric, and material properties of cortical bone in a transgenic mouse model overexpressing DMP1. Micro-computed tomography and three-point bending were performed on 90 femora of wild t...

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Detalhes bibliográficos
Main Authors: Bhatia, Ankush, Albazzaz, Michael, Espinoza Orías, Alejandro A., Inoue, Nozomu, Miller, Lisa M., Acerbo, Alvin, George, Anne, Sumner, Dale R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222863/
https://ncbi.nlm.nih.gov/pubmed/22100074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2011.08.026
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