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The Heritability of Amyotrophic Lateral Sclerosis in a Clinically Ascertained United States Research Registry

BACKGROUND: The genetic basis of amyotrophic lateral sclerosis (ALS) is not entirely clear. While there are families with rare highly penetrant mutations in Cu/Zn superoxide dismutase 1 and several other genes that cause apparent Mendelian inheritance of the disease, most ALS occurs in families with...

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Bibliografische gegevens
Hoofdauteurs: Wingo, Thomas S., Cutler, David J., Yarab, Nicole, Kelly, Crystal M., Glass, Jonathan D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222666/
https://ncbi.nlm.nih.gov/pubmed/22132186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027985
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