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Normalization of High Dimensional Genomics Data Where the Distribution of the Altered Variables Is Skewed

Genome-wide analysis of gene expression or protein binding patterns using different array or sequencing based technologies is now routinely performed to compare different populations, such as treatment and reference groups. It is often necessary to normalize the data obtained to remove technical var...

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Detalhes bibliográficos
Main Authors: Landfors, Mattias, Philip, Philge, Rydén, Patrik, Stenberg, Per
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222656/
https://ncbi.nlm.nih.gov/pubmed/22132175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027942
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