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Normalization of High Dimensional Genomics Data Where the Distribution of the Altered Variables Is Skewed
Genome-wide analysis of gene expression or protein binding patterns using different array or sequencing based technologies is now routinely performed to compare different populations, such as treatment and reference groups. It is often necessary to normalize the data obtained to remove technical var...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222656/ https://ncbi.nlm.nih.gov/pubmed/22132175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027942 |
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