QTL Analysis Identifies a Modifier Locus of Aganglionosis in the Rat Model of Hirschsprung Disease Carrying Ednrb(sl) Mutations

Hirschsprung disease (HSCR) exhibits complex genetics with incomplete penetrance and variable severity thought to result as a consequence of multiple gene interactions that modulate the ability of enteric neural crest cells to populate the developing gut. As reported previously, when the same null m...

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Bibliografiske detaljer
Main Authors: Dang, Ruihua, Torigoe, Daisuke, Sasaki, Nobuya, Agui, Takashi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222640/
https://ncbi.nlm.nih.gov/pubmed/22132166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027902
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