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A Lipopeptide Facilitate Induction of Mycobacterium leprae Killing in Host Cells

Little is known of the direct microbicidal activity of T cells in leprosy, so a lipopeptide consisting of the N-terminal 13 amino acids lipopeptide (LipoK) of a 33-kD lipoprotein of Mycobacterium leprae, was synthesized. LipoK activated M. leprae infected human dendritic cells (DCs) to induce the pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maeda, Yumi, Tamura, Toshiki, Fukutomi, Yasuo, Mukai, Tetsu, Kai, Masanori, Makino, Masahiko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222628/
https://ncbi.nlm.nih.gov/pubmed/22132248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001401
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