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AAV8-mediated Hepatic Gene Transfer in Infant Rhesus Monkeys (Macaca mulatta)

Many genetic metabolic diseases manifest in infancy, therefore, it is important to develop effective treatments that could be implemented at this time. Adeno-associated virus serotype 8 (AAV8) gene transfer has been studied in neonatal mouse, cat, and dog models and shown some efficacy with a single...

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Detalhes bibliográficos
Main Authors: Wang, Lili, Bell, Peter, Lin, Jianping, Calcedo, Roberto, Tarantal, Alice F, Wilson, James M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222523/
https://ncbi.nlm.nih.gov/pubmed/21811248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.151
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