Cortical and Hippocampal Atrophy in Patients with Autosomal Dominant Familial Alzheimer's Disease

BACKGROUND: Both familial and sporadic Alzheimer's disease (AD) result in progressive cortical and subcortical atrophy. Familial autosomal dominant AD (FAD) allows us to study AD brain changes presymptomatically. METHODS: 33 subjects at risk for FAD (25 for PSEN1 and 8 for APP mutations; 22 mut...

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Bibliografiske detaljer
Main Authors: Apostolova, Liana G., Hwang, Kristy S., Medina, Luis D., Green, Amity E., Braskie, Meredith N., Dutton, Rebecca A., Lai, Jeffrey, Geschwind, Daniel H., Cummings, Jeffrey L., Thompson, Paul M., Ringman, John M.
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2011
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222115/
https://ncbi.nlm.nih.gov/pubmed/21952501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330471
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