Circulating adenosine increases during human experimental endotoxemia but blockade of its receptor does not influence the immune response and subsequent organ injury

INTRODUCTION: Preclinical studies have shown that the endogenous nucleoside adenosine prevents excessive tissue injury during systemic inflammation. We aimed to study whether endogenous adenosine also limits tissue injury in a human in vivo model of systemic inflammation. In addition, we studied whe...

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Detalhes bibliográficos
Main Authors: Ramakers, Bart P, Riksen, Niels P, van den Broek, Petra, Franke, Barbara, Peters, Wilbert HM, van der Hoeven, Johannes G, Smits, Paul, Pickkers, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222030/
https://ncbi.nlm.nih.gov/pubmed/21211004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9400
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