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Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b(+)Gr1(+) cells

Extracellular adenosine and purine nucleotides are elevated in many pathological situations associated with the expansion of CD11b(+)Gr1(+) myeloid-derived suppressor cells (MDSCs). Therefore, we tested whether adenosinergic pathways play a role in MDSC expansion and functions. We found that A(2B) a...

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Detalhes bibliográficos
Main Authors: Ryzhov, Sergey, Novitskiy, Sergey V., Goldstein, Anna E., Biktasova, Asel, Blackburn, Michael R., Biaggioni, Italo, Dikov, Mikhail M., Feoktistov, Igor
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221925/
https://ncbi.nlm.nih.gov/pubmed/22039302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101225
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