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Glycogen Synthase Kinase-3β is a pro-survival signal for the maintenance of human mast cell homeostasis

Homeostasis of mature tissue-resident mast cells is dependent on the relative activation of pro- and anti-apoptotic regulators. In this study we investigated the role of Glycogen Synthase Kinase-3β (GSK3β) in the survival of neoplastic and non-neoplastic human mast cells. GSK3β was observed to be ph...

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Detalhes bibliográficos
Main Authors: Rådinger, Madeleine, Smrž, Daniel, Metcalfe, Dean D., Gilfillan, Alasdair M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221874/
https://ncbi.nlm.nih.gov/pubmed/22039301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101257
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