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The Discovery of Carboxyethylpyrroles (CEPs): Critical Insights into AMD, Autism, Cancer, and Wound Healing from Basic Research on the Chemistry of Oxidized Phospholipids

Basic research, exploring the hypothesis that 2-(ω-carboxyethyl)pyrrole (CEP) modifications of proteins are generated nonenzymatically in vivo is delivering a bonanza of molecular mechanistic insights into age-related macular degeneration, autism, cancer, and wound healing. CEPs are produced through...

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Detalhes bibliográficos
Main Authors: Salomon, Robert G., Hong, Li, Hollyfield, Joe G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221790/
https://ncbi.nlm.nih.gov/pubmed/21875030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx200206v
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