Accessing Stereochemically Rich Sultams via Microwave-Assisted, Continuous Flow Organic Synthesis (MACOS) Scale-out

The generation of stereochemically-rich benzothiaoxazepine-1,1′-dioxides for enrichment of high-throughput screening collections is reported. Utilizing a microwave-assisted, continuous flow organic synthesis platform (MACOS), scale-out of core benzothiaoxazepine-1,1′-dioxide scaffolds has been achie...

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Bibliographic Details
Main Authors: Organ, Michael G., Hanson, Paul R., Rolfe, Alan, Samarakoon, Thiwanka B., Ullah, Farman
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221740/
https://ncbi.nlm.nih.gov/pubmed/22116791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/jfchem.2011.00008
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