Multiple Cytokines Are Released When Blood from Patients with Tuberculosis Is Stimulated with Mycobacterium tuberculosis Antigens

BACKGROUND: Mycobacterium tuberculosis (Mtb) infection may cause overt disease or remain latent. Interferon gamma release assays (IGRAs) detect Mtb infection, both latent infection and infection manifesting as overt disease, by measuring whole-blood interferon gamma (IFN-γ) responses to Mtb antigens...

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Detalhes bibliográficos
Main Authors: Kellar, Kathryn L., Gehrke, Jennifer, Weis, Stephen E., Mahmutovic-Mayhew, Aida, Davila, Blachy, Zajdowicz, Margan J., Scarborough, Robin, LoBue, Philip A., Lardizabal, Alfred A., Daley, Charles L., Reves, Randall R., Bernardo, John, Campbell, Brandon H., Whitworth, William C., Mazurek, Gerald H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221668/
https://ncbi.nlm.nih.gov/pubmed/22132075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026545
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