The new platinum-based anticancer agent LA-12 induces retinol binding protein 4 in vivo

BACKGROUND: The initial pharmacokinetic study of a new anticancer agent (OC-6-43)-bis(acetato)(1-adamantylamine)amminedichloroplatinum (IV) (LA-12) was complemented by proteomic screening of rat plasma. The objective of the study was to identify new LA-12 target proteins that serve as markers of LA-...

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Autors principals: Bouchal, Pavel, Jarkovsky, Jiri, Hrazdilova, Kristyna, Dvorakova, Monika, Struharova, Iva, Hernychova, Lenka, Damborsky, Jiri, Sova, Petr, Vojtesek, Borivoj
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221626/
https://ncbi.nlm.nih.gov/pubmed/22040120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5956-9-68
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