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Quantifying the impact of chimera MS/MS spectra on peptide identification in large scale proteomics studies
A complicating factor for protein identification within complex mixtures by LC/MS/MS is the problem of “chimera” spectra, where two or more precursor ions with similar mass and retention time are co-sequenced by MS/MS. Chimera spectra show reduced scores due to unidentifiable fragment ions derived f...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221600/ https://ncbi.nlm.nih.gov/pubmed/20578722 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr1003856 |
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