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Differential inhibition of human placental DNA polymerases delta and alpha by BuPdGTP and BuAdATP.
The p-n-butylphenyl- and p-n-butylanilino- substituted analogs of dGTP and dATP, respectively, were tested as inhibitors of purified human placental DNA polymerases alpha and delta. It was observed that DNA polymerase alpha activity was potently inhibited by these analogs with I0.5 values as low as...
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| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1985
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC322157/ https://ncbi.nlm.nih.gov/pubmed/3936020 |
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