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A Data Analysis Strategy for Maximizing High-confidence Protein Identifications in Complex Proteomes Such as Human Tumor Secretomes and Human Serum
Detection of biologically interesting, low-abundance proteins in complex proteomes such as serum typically requires extensive fractionation and high-performance mass spectrometers. Processing of the resulting large datasets involves trade-offs between confidence of identification and depth of protei...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221390/ https://ncbi.nlm.nih.gov/pubmed/21955121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200464c |
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