Analytical studies of 'mixed sequence' oligodeoxyribonucleotides synthesized by competitive coupling of either methyl- or beta-cyanoethyl-N,N-diisopropylamino phosphoramidite reagents, including 2'-deoxyinosine.

High-performance liquid chromatography (HPLC) and 1H/31P nuclear magnetic resonance (NMR) spectroscopy were used to measure the molar ratio of oligodeoxyribonucleotide products in mixtures obtained with automated DNA synthesizers that employed competitive coupling of either standard methyl- or newer...

Full description

Saved in:
Bibliographic Details
Main Authors: Zon, G, Gallo, K A, Samson, C J, Shao, K L, Summers, M F, Byrd, R A
Format: Artigo
Language:Inglês
Published: 1985
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC322118/
https://ncbi.nlm.nih.gov/pubmed/4070002
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items