Neuroprotective efficacy of caramiphen against soman and mechanisms of its action

BACKGROUND AND PURPOSE: Caramiphen is a muscarinic antagonist with potent anticonvulsant properties. Here, we investigated the efficacy of caramiphen against behavioural seizures and neuropathology induced by the nerve agent soman, and revealed two mechanisms that may underlie the anticonvulsant eff...

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Detalhes bibliográficos
Main Authors: Figueiredo, TH, Aroniadou-Anderjaska, V, Qashu, F, Apland, JP, Pidoplichko, V, Stevens, D, Ferrara, TM, Braga, MFM
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221103/
https://ncbi.nlm.nih.gov/pubmed/21486285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01427.x
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