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Mechanical stiffness grades metastatic potential in patient tumor cells and in cancer cell lines

Cancer cells are defined by their ability to invade through the basement membrane, a critical step during metastasis. While increased secretion of proteases, which facilitates degradation of the basement membrane, and alterations in the cytoskeletal architecture of cancer cells have been previously...

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Detalhes bibliográficos
Main Authors: Swaminathan, Vinay, Mythreye, Karthikeyan, O’Brien, E Tim, Berchuck, Andrew, Blobe, Gerard C, Superfine, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220953/
https://ncbi.nlm.nih.gov/pubmed/21642375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-0247
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