Group I mGluR Activation Reverses Cocaine-Induced Accumulation of Calcium-Permeable AMPA Receptors in Nucleus Accumbens Synapses via a Protein Kinase C-Dependent Mechanism

Following prolonged withdrawal from extended access cocaine self-administration in adult rats, high conductance Ca(2+)-permeable AMPA receptors (CP-AMPARs) accumulate in nucleus accumbens (NAc) synapses and mediate the expression of “incubated” cue-induced cocaine craving. Using patch-clamp recordin...

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Autors principals: McCutcheon, James E., Loweth, Jessica A., Ford, Kerstin A., Marinelli, Michela, Wolf, Marina E., Tseng, Kuei Y.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2011
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220940/
https://ncbi.nlm.nih.gov/pubmed/21994370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3625-11.2011
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