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Mechanisms of ER Stress-induced Apoptosis in Atherosclerosis

Endoplasmic reticulum (ER) stress is triggered by perturbations in ER function such as those caused by protein misfolding or by increases in protein secretion. Eukaryotic cells respond to ER stress by activating three ER-resident proteins, ATF6, IRE1, and PERK. These proteins direct signaling pathwa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Scull, Christopher M., Tabas, Ira
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220876/
https://ncbi.nlm.nih.gov/pubmed/22096099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.224881
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