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Mechanisms of ER Stress-induced Apoptosis in Atherosclerosis
Endoplasmic reticulum (ER) stress is triggered by perturbations in ER function such as those caused by protein misfolding or by increases in protein secretion. Eukaryotic cells respond to ER stress by activating three ER-resident proteins, ATF6, IRE1, and PERK. These proteins direct signaling pathwa...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220876/ https://ncbi.nlm.nih.gov/pubmed/22096099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.224881 |
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