Pharmacokinetics and Pharmacodynamics of High-Dose Human Regular U-500 Insulin Versus Human Regular U-100 Insulin in Healthy Obese Subjects

OBJECTIVE: Human regular U-500 (U-500R) insulin (500 units/mL) is increasingly being used clinically, yet its pharmacokinetics (PK) and pharmacodynamics (PD) have not been well studied. Therefore, we compared PK and PD of clinically relevant doses of U-500R with the same doses of human regular U-100...

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Détails bibliographiques
Auteurs principaux: de la Peña, Amparo, Riddle, Matthew, Morrow, Linda A., Jiang, Honghua H., Linnebjerg, Helle, Scott, Adam, Win, Khin M., Hompesch, Marcus, Mace, Kenneth F., Jacobson, Jennie G., Jackson, Jeffrey A.
Format: Artigo
Langue:Inglês
Publié: American Diabetes Association 2011
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220843/
https://ncbi.nlm.nih.gov/pubmed/21994429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc11-0721
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