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Bacterial DNA Induces Pulmonary Damage via TLR9 through Cross-Talk with Neutrophils

Bacterial DNA (bDNA) contains hypo-methylated “CpG” repeats that can be recognized by toll-like receptor (TLR)-9 as a pathogen-associated molecular pattern (PAMP). The ability of bDNA to initiate lung injury via TLR-9 has been inferred on the basis of studies using artificial CpG DNA. But the role o...

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Détails bibliographiques
Auteurs principaux: Itagaki, Kiyoshi, Adibnia, Yasaman, Sun, Shiqin, Zhao, Cong, Sursal, Tolga, Chen, Yu, Junger, Wolfgang, Hauser, Carl J.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220777/
https://ncbi.nlm.nih.gov/pubmed/21937948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3182369fb2
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