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(+)-Morphine attenuates the (−)-morphine-produced tail-flick inhibition via the sigma-1 receptor in the mouse spinal cord

AIMS: We have previously demonstrated that pretreatment with (+)-morphine given intrathecally attenuates the intrathecal (−)-morphine-produced tail-flick inhibition. The phenomenon has been defined as antianalgesia against (−)-morphine-produced analgesia. Present experiments were then undertaken to...

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Autori principali: Tseng, Leon F., Hogan, Quinn H., Wu, Hsiang-En
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220751/
https://ncbi.nlm.nih.gov/pubmed/21989208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2011.09.018
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