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Activated Platelets in Heparinized Shed Blood: The “Second-Hit” of Acute Lung Injury in Trauma/Hemorrhagic Shock Models

BACKGROUND: The return of heparinized shed blood in trauma/hemorrhagic shock (T/HS) models remains controversial due to potential anti-inflammatory properties. Although ubiquitous as an anticoagulant, heparin is ineffective on cellular coagulation as an antithrombotic agent. Therefore, we hypothesiz...

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Main Authors: Harr, Jeffrey N., Moore, Ernest E., Wohlauer, Max V., Fragoso, Miguel, Gamboni, Fabia, Liang, Xiayuan, Banerjee, Anirban, Silliman, Christopher C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220733/
https://ncbi.nlm.nih.gov/pubmed/21841533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e318231ee76
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