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Endogenously Expressed Muscarinic Receptors in HEK293 Cells Augment Up-regulation of Stably Expressed α4β2 Nicotinic Receptors

Nicotine-induced up-regulation of neuronal nicotinic receptors (nAChRs) has been known and studied for more than 25 years. Other nAChR ligands can also up-regulate nAChRs, but it is not known if these ligands induce up-regulation by mechanisms similar to that of nicotine. In this study, we compared...

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Autors principals: Hussmann, Gregory P., Yasuda, Robert P., Xiao, Yingxian, Wolfe, Barry B., Kellar, Kenneth J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220562/
https://ncbi.nlm.nih.gov/pubmed/21940627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.289546
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