Relative Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Tumor Necrosis Factor-α (TNF-α)-induced Lipolysis in Adipocytes

TNF-α potently stimulates basal lipolysis in adipocytes, which may contribute to hyperlipidemia and peripheral insulin resistance in obesity. Recent studies show that adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) act sequentially in catalyzing the first two steps of adipose l...

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Bibliographic Details
Main Authors: Yang, Xingyuan, Zhang, Xiaodong, Heckmann, Bradlee L., Lu, Xin, Liu, Jun
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220500/
https://ncbi.nlm.nih.gov/pubmed/21969372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.257923
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