Regulation of β(2)-Adrenergic Receptor Maturation and Anterograde Trafficking by an Interaction with Rab Geranylgeranyltransferase: MODULATION OF Rab GERANYLGERANYLATION BY THE RECEPTOR

Previous reports by us and others demonstrated that G protein-coupled receptors interact functionally with Rab GTPases. Here, we show that the β(2)-adrenergic receptor (β(2)AR) interacts with the Rab geranylgeranyltransferase α-subunit (RGGTA). Confocal microscopy showed that β(2)AR co-localizes wit...

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Detalhes bibliográficos
Main Authors: Lachance, Véronik, Cartier, Andréane, Génier, Samuel, Munger, Sandra, Germain, Pascale, Labrecque, Pascale, Parent, Jean-Luc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220499/
https://ncbi.nlm.nih.gov/pubmed/21990357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.267815
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