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Modulating O(2) Reactivity in a Fungal Flavoenzyme: INVOLVEMENT OF ARYL-ALCOHOL OXIDASE PHE-501 CONTIGUOUS TO CATALYTIC HISTIDINE

Aryl-alcohol oxidase (AAO) is a flavoenzyme responsible for activation of O(2) to H(2)O(2) in fungal degradation of lignin. The AAO crystal structure shows a buried active site connected to the solvent by a hydrophobic funnel-shaped channel, with Phe-501 and two other aromatic residues forming a nar...

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Détails bibliographiques
Auteurs principaux: Hernández-Ortega, Aitor, Lucas, Fátima, Ferreira, Patricia, Medina, Milagros, Guallar, Victor, Martínez, Angel T.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220487/
https://ncbi.nlm.nih.gov/pubmed/21940622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.282467
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