Relationship between cytomegalovirus (CMV) IgG serology, detectable CMV DNA in peripheral monocytes, and CMV pp65(495–503)-specific CD8(+) T cells in older adults

In immunocompetent individuals, cytomegalovirus (CMV) is thought to persist in a latent state in monocytes and myeloid progenitor cells, establishing a lifelong infection. In CMV-seropositive older adults, aging has been associated with both expansion of CMV pp65(495–503)-specific CD8(+) T cell clon...

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Hauptverfasser: Leng, Sean X., Qu, Tao, Semba, Richard D., Li, Huifen, Yao, Xu, Nilles, Tricia, Yang, Xi, Manwani, Bhavish, Walston, Jeremy D., Ferrucci, Luigi, Fried, Linda P., Margolick, Joseph B., Bream, Jay H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220402/
https://ncbi.nlm.nih.gov/pubmed/21274637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-011-9205-9
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