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A cell model to study different degrees of Hsp60 deficiency in HEK293 cells
Mitochondrial dysfunction is associated with neurodegenerative diseases and mutations in the HSPD1 gene, encoding the mitochondrial Hsp60 chaperone, are the causative factors of two neurodegenerative diseases, hereditary spastic paraplegia and MitChap60 disease. In cooperation with Hsp10, Hsp60 form...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3220388/ https://ncbi.nlm.nih.gov/pubmed/21717087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-011-0275-5 |
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