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Germline Stem Cells

Sperm and egg production requires a robust stem cell system that balances self-renewal with differentiation. Self-renewal at the expense of differentiation can cause tumorigenesis, whereas differentiation at the expense of self-renewal can cause germ cell depletion and infertility. In most organisms...

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Detalhes bibliográficos
Main Authors: Spradling, Allan, Fuller, Margaret T., Braun, Robert E., Yoshida, Shosei
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220357/
https://ncbi.nlm.nih.gov/pubmed/21791699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a002642
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