Honokiol radiosensitizes colorectal cancer cells: enhanced activity in cells with mismatch repair defects

DNA mismatch repair is required for correcting any mismatches that are created during replication and recombination, and a defective mismatch repair system contributes to DNA damage-induced growth arrest. The colorectal cancer cell line HCT116 is known to have a mutation in the hMLH1 mismatch repair...

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Autori principali: He, Zhiyun, Subramaniam, Dharmalingam, Ramalingam, Satish, Dhar, Animesh, Postier, Russell G., Umar, Shahid, Zhang, Youcheng, Anant, Shrikant
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2011
Soggetti:
Cancer Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220322/
https://ncbi.nlm.nih.gov/pubmed/21836060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00159.2011
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