Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition

Although there are small animal platforms that recapitulate some of the histological features of nonalcoholic fatty liver disease, there are no small animal models of nonalcoholic steatohepatitis (NASH) with consistent hepatocellular ballooning and progressive fibrosis that also exhibit fidelity to...

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Hlavní autoři: Charlton, Michael, Krishnan, Anuradha, Viker, Kimberly, Sanderson, Schuyler, Cazanave, Sophie, McConico, Andrea, Masuoko, Howard, Gores, Gregory
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2011
Témata:
Liver and Biliary Tract
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220319/
https://ncbi.nlm.nih.gov/pubmed/21836057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00145.2011
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