Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition

Although there are small animal platforms that recapitulate some of the histological features of nonalcoholic fatty liver disease, there are no small animal models of nonalcoholic steatohepatitis (NASH) with consistent hepatocellular ballooning and progressive fibrosis that also exhibit fidelity to...

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Bibliographic Details
Main Authors: Charlton, Michael, Krishnan, Anuradha, Viker, Kimberly, Sanderson, Schuyler, Cazanave, Sophie, McConico, Andrea, Masuoko, Howard, Gores, Gregory
Format: Artigo
Language:Inglês
Published: American Physiological Society 2011
Subjects:
Liver and Biliary Tract
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220319/
https://ncbi.nlm.nih.gov/pubmed/21836057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00145.2011
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