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On-Chip Evaluation of Shear Stress Effect on Cytotoxicity of Mesoporous Silica Nanoparticles

In this work, nanotoxicity in the bloodstream was modeled and the cytotoxicity of sub-50 nm mesoporous silica nanoparticles to human endothelial cells was investigated under microfluidic flow conditions. Compared to traditional in vitro cytotoxicity assays performed under static conditions, unmodifi...

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Detalhes bibliográficos
Main Authors: Kim, Donghyuk, Lin, Yu-Shen, Haynes, Christy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220276/
https://ncbi.nlm.nih.gov/pubmed/22032307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac202115a
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