Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats

INTRODUCTION: Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), the major endothelial receptor for oxidized low-density lipoprotein, is also involved in leukocyte recruitment. Systemic leukocyte activation in sepsis represents a crucial factor in the impairment of the microcirculation...

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Main Authors: Landsberger, Martin, Zhou, Juan, Wilk, Sebastian, Thaumüller, Corinna, Pavlovic, Dragan, Otto, Marion, Whynot, Sara, Hung, Orlando, Murphy, Michael F, Cerny, Vladimir, Felix, Stephan B, Lehmann, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220004/
https://ncbi.nlm.nih.gov/pubmed/21143965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9367
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