Negative regulation of inflammatory responses by immunoglobulin A receptor (FcαRI) inhibits the development of Toll-like receptor-9 signalling-accelerated glomerulonephritis

Myeloid FcαRI, a receptor for immunoglobulin (Ig)A, mediates cell activation or inhibition depending on the type of ligand interaction, which can be either multivalent or monovalent. Anti-inflammatory signalling is triggered by monomeric targeting using anti-FcαRI Fab or IgA ligand binding, which in...

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Библиографические подробности
Главные авторы: Watanabe, T, Kanamaru, Y, Liu, C, Suzuki, Y, Tada, N, Okumura, K, Horikoshi, S, Tomino, Y
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2011
Предметы:
Translational Studies
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219899/
https://ncbi.nlm.nih.gov/pubmed/21985370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04452.x
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