Altered phenotype of regulatory T cells associated with lack of human immunodeficiency virus (HIV)-1-specific suppressive function

Mechanisms by which CD4(+) regulatory T cells (T(regs)) mediate suppression of virus-specific responses remain poorly defined. Adenosine, mediated via CD39 and CD73, has been shown to play a role in the action of murine T(regs). In this study we investigate the phenotype of T(regs) in the context of...

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Detalhes bibliográficos
Main Authors: Burton, C T, Westrop, S J, Eccles-James, I, Boasso, A, Nelson, M R, Bower, M, Imami, N
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Translational Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219894/
https://ncbi.nlm.nih.gov/pubmed/21985365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2011.04451.x
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