Indirect DNA Readout by an H-NS Related Protein: Structure of the DNA Complex of the C-Terminal Domain of Ler

Ler, a member of the H-NS protein family, is the master regulator of the LEE pathogenicity island in virulent Escherichia coli strains. Here, we determined the structure of a complex between the DNA-binding domain of Ler (CT-Ler) and a 15-mer DNA duplex. CT-Ler recognizes a preexisting structural pa...

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Bibliographic Details
Main Authors: Cordeiro, Tiago N., Schmidt, Holger, Madrid, Cristina, Juárez, Antonio, Bernadó, Pau, Griesinger, Christian, García, Jesús, Pons, Miquel
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219716/
https://ncbi.nlm.nih.gov/pubmed/22114557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002380
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