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The N-Terminal Domain and Glycosomal Localization of Leishmania Initial Acyltransferase LmDAT Are Important for Lipophosphoglycan Synthesis

Ether glycerolipids of Leishmania major are important membrane components as well as building blocks of various virulence factors. In L. major, the first enzyme of the ether glycerolipid biosynthetic pathway, LmDAT, is an unusual, glycosomal dihydroxyacetonephosphate acyltransferase important for pa...

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Detalhes bibliográficos
Main Authors: Al-Ani, Gada K., Patel, Nipul, Pirani, Karim A., Zhu, Tongtong, Dhalladoo, Subbhalakshmi, Zufferey, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219689/
https://ncbi.nlm.nih.gov/pubmed/22114698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027802
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