Evidence-Based Annotation of Gene Function in Shewanella oneidensis MR-1 Using Genome-Wide Fitness Profiling across 121 Conditions

Most genes in bacteria are experimentally uncharacterized and cannot be annotated with a specific function. Given the great diversity of bacteria and the ease of genome sequencing, high-throughput approaches to identify gene function experimentally are needed. Here, we use pools of tagged transposon...

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Main Authors: Deutschbauer, Adam, Price, Morgan N., Wetmore, Kelly M., Shao, Wenjun, Baumohl, Jason K., Xu, Zhuchen, Nguyen, Michelle, Tamse, Raquel, Davis, Ronald W., Arkin, Adam P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219624/
https://ncbi.nlm.nih.gov/pubmed/22125499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002385
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