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Speed, Sensitivity, and Bistability in Auto-activating Signaling Circuits
Cells employ a myriad of signaling circuits to detect environmental signals and drive specific gene expression responses. A common motif in these circuits is inducible auto-activation: a transcription factor that activates its own transcription upon activation by a ligand or by post-transcriptional...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219618/ https://ncbi.nlm.nih.gov/pubmed/22125482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002265 |
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