Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients

INTRODUCTION: Septic shock remains a major health care problem worldwide. Sepsis-induced immune alterations are thought to play a major role in patients' mortality and susceptibility to nosocomial infections. Programmed death-1 (PD-1) receptor system constitutes a newly described immunoregulato...

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Hlavní autoři: Guignant, Caroline, Lepape, Alain, Huang, Xin, Kherouf, Hakim, Denis, Laure, Poitevin, Françoise, Malcus, Christophe, Chéron, Aurélie, Allaouchiche, Bernard, Gueyffier, François, Ayala, Alfred, Monneret, Guillaume, Venet, Fabienne
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219369/
https://ncbi.nlm.nih.gov/pubmed/21418617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10112
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