Cloned DNA sequences that determine mRNA stability of bacteriophage phi X174 in vivo are functional.
The stability of two species of phi X174 polycistronic mRNA in vivo can be altered by mutating sequences existing immediately upstream of a termination site. The wild type phage contains an mRNA stabilizing sequence ((+) sequence), while the same sequence mutated by insertion ((-) sequence) reduces...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1985
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC321924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2994019/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/13.16.5937 |
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