Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state

Direct reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) provides a unique opportunity to derive patient-specific stem cells with potential applications in tissue replacement therapies and without the ethical concerns of human embryonic stem cells (hESCs). However, cellular...

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Hauptverfasser: Lapasset, Laure, Milhavet, Ollivier, Prieur, Alexandre, Besnard, Emilie, Babled, Amelie, Aït-Hamou, Nafissa, Leschik, Julia, Pellestor, Franck, Ramirez, Jean-Marie, De Vos, John, Lehmann, Sylvain, Lemaitre, Jean-Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2011
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219229/
https://ncbi.nlm.nih.gov/pubmed/22056670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.173922.111
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