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Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state
Direct reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) provides a unique opportunity to derive patient-specific stem cells with potential applications in tissue replacement therapies and without the ethical concerns of human embryonic stem cells (hESCs). However, cellular...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3219229/ https://ncbi.nlm.nih.gov/pubmed/22056670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.173922.111 |
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