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Pioneer transcription factors: establishing competence for gene expression

Transcription factors are adaptor molecules that detect regulatory sequences in the DNA and target the assembly of protein complexes that control gene expression. Yet much of the DNA in the eukaryotic cell is in nucleosomes and thereby occluded by histones, and can be further occluded by higher-orde...

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Autori principali: Zaret, Kenneth S., Carroll, Jason S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219227/
https://ncbi.nlm.nih.gov/pubmed/22056668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.176826.111
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