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A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast

In most mammalian species, a critical step of placenta development is the fusion of trophoblast cells into a multinucleated syncytiotrophoblast layer fulfilling essential fetomaternal exchange functions. Key insights into this process came from the discovery of envelope genes of retroviral origin, t...

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Detalhes bibliográficos
Main Authors: Dupressoir, Anne, Vernochet, Cécile, Harper, Francis, Guégan, Justine, Dessen, Philippe, Pierron, Gérard, Heidmann, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219115/
https://ncbi.nlm.nih.gov/pubmed/22032925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1112304108
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